Steroid hormones are lipids and originate from a common precursor: cholesterol. Transformation of cholesterol to steroid hormones has an extreme physiological importance. Steroid hormones are involved in metabolism, growth and reproduction. They are in the circulatory flow, transported by specific proteins named carriers, allowing the hormone to reach its target.
Spontaneous or inherited genetic mutations that may affect the synthesis of these enzymes are responsible of the alteration of normal levels of steroid hormones. Disorders of organs involved insteroids production and regulation can also bring to a steroid pathological level. It is useful to determinate steroid hormones profile rather than individual steroid analyte.