VDSpher® MS Column Line
Mass spectrometry is being used by an increased number of clinical laboratories to handle small sample volumes in order to detect and quantify very small concentrations of a given analyte such as Vitamin D2/D3, Immunosuppressants, etc. The HPLC column is an essential part of an LC-MS/MS configuration and needs to fulfill certain criteria:
- Particle size of 2.5 μm if a high resolution is needed.
- Particel size of 4.0 μm if the resolution is not an issue.
Since Mass Spectrometry is a highly sensitive method, very small impurities can be detected (e.g. due to carry-over effects), the VDSpher® MS phases were specifically designed in order to avoid these carry-over effects.
We are introducing 10 different modifications of the VDSpher® MS line.
The C18 phases can be used for a broad range of
- hydrophilic (C18-H, C18-LC-H) and
- hydrophobic (C18-DE, C18-B-DE) applications.
The non-endcapped phase C18-B shows a medium hydrophobicity.
In addition, we offer
- hydrophobic VDSpher® MS-Phases with C8, C4, Phenyl und CN- modifications.
The pore diameter of all VDSpher® MS-Phases is 100 Å and the column dimensions available are 30-150 mm length and 2.0 - 4.6 mm ID. Longer columns are available upon request.
Phase |
Endcapping |
pH Range |
USP-Code |
VDSpher® MS 100 C18-DE |
Yes |
2 – 9 |
L1 |
VDSpher® MS 100 C18-B |
No |
2 – 7.5 |
L1 |
VDSpher® MS 100 C18-B-DE |
Yes |
2 – 10 |
L1 |
VDSpher® MS 100 C18-H |
Polar |
2 – 7.5 |
L1 |
VDSpher® MS 100 C18-LC-H |
Hydrophilic |
2 – 8 |
L1 |
VDSpher® MS 100 C8-B-DE |
Yes |
2 – 10 |
L7 |
VDSpher® MS 100 C4-B-DE |
Yes |
2 – 9 |
L26 |
VDSpher® MS 100 Phenyl-DE |
Yes |
2 – 9 |
L11 |
VDSpher® MS 100 CN-DE |
Yes |
2 – 9 |
L10 |
VDSpher® MS 100 CN-DE-RP |
Yes |
2 – 9 |
L10 |
VDSpher® MS 100 HPLC-Columns Phase Codes
Phase |
Particle Size: 2.5 μm |
Particle Size: 4.0 μm |
C18-DE |
E18BVMF |
E18BVMI |
C18-B |
E189VMF |
E189VMI |
C18-B-DE |
E18DVMF |
E18DVMI |
C18-H |
E184VMF |
E184VMI |
C18-LC-H |
E18HVMF |
E18HVMI |
C8-B-DE |
E08DVMF |
E08DVMI |
C4-B-DE |
E04DVMF |
E04DVMI |
Phenyl-DE |
E05BVMF |
E05BVMI |
CN-DE |
E20BVMF |
E20BVMI |
CN-DE-RP |
E21BVMF |
E21BVMI |
VDSpher® ME 100 - Columns & Guard Cartridges / Dimension Codes
ID in mm |
Length in mm |
Dimension Code |
2.0 |
30 |
N0320… |
33 |
N0420… |
|
50 |
N0520… |
|
53 |
N0620… |
|
75 |
N0720… |
|
100 |
N1020… |
|
125 |
N1320… |
|
150 |
N1520… |
|
3.0 |
30 |
N0330… |
33 |
N0430… |
|
50 |
N0530… |
|
53 |
N0630… |
|
75 |
N0730… |
|
100 |
N1030… |
|
125 |
N1330… |
|
150 |
N1530… |
|
4.0 |
30 |
N0340… |
33 |
N0440… |
|
50 |
N0540… |
|
53 |
N0640… |
|
75 |
N0740… |
|
100 |
N1040… |
|
125 |
N1340… |
|
150 |
N1540… |
|
4.6 |
30 |
N0346… |
33 |
N0446… |
|
50 |
N0546… |
|
53 |
N0646… |
|
75 |
N0746… |
|
100 |
N1046… |
|
125 |
N1346… |
|
150 |
N1546… |
|
2.0 |
5 |
V0520… |
10 |
V1020… |
|
4.0 |
5 |
V0540… |
10 |
V1040… |
Example: VDSpher® MS 100 C18-B 2.5 μm, 50 x 2.0 mm
Dimension Code: N0520 + Phase Code: E189VMF
Order No.: N0520E189VMF
For further information please contact us at info@iristech.net.